Chapter-20
Locomotion and Movement
- Points to Remember
- Arthritis : An inflammatory joint disease characteristics by inflammation of joints.
- Coccyx : Tail bone fomed by fusion of four coccygeal vertebrae in man.
- Dicodylic Skull : A skull with two occipital condyles.
- Endo Skeleton : A skeletons present in side the body.
- Fascicle : Bundles of muscules fibres held together by connective tissue.
- Fascia : Collagenous connective tissue layer that surrounds muscule bundles.
- Floating ribs : The ribs that remain free anteriorly, (last 2 paris)
- False ribs : 8th, 9th and 10th pair of ribs not directly joins the sternum but the seventh pair of ribs, hence called pseudoribs.
- Myoglobin : A red colored pigment present in sarcoplasm of muscle.
- Sarcomere : A portion of myofibril between tow successive 'Z' lines.
- Sarcolema : The plasma membrane of a muscle.
- Gout : Inflammation of joins due to accumulation of uric acid crystal.
- Suture : Immovable joins between limb bones.
- Patella : A seasmoid bone acting as kneecap.
- Intervertebral disc : Fibro cartilaginous pad present between the vertebrae that act as shock absorbers.
- Tendon - Connective tissue made of yellow fibrous tissue which connect muscle to bone. It is not flexible.
- Ligament - Connective tissue made of white fibrous tissue which joins two bones. It is flexible.
- LMM : Light Meromyosin
- HMM : Heavy Meromyosin
Types of Movement :
- 1. Amoeboid Movement : These movement takes place in phagocytes where leucocytes and macrophages migrate through tissue. It is affected by pseudepodia formed by the streaming of protoplasm (as in amoeba)
- 2. Ciliary Movement : These movement occurs in internal organs which are lined by ciliary epithelium.
- 3. Muscular Movement : This movements involve the muscle fibers, which have the abililty to contract and relax.
- Properties of Muscle : (i) Excitability (ii) Contractility
(iii) Extensibility (iv) Elasticiyt
Type of Muscles :
- (a) Skeletal Muscles or Striated Muscles - These involved in locomotion and change of body postures. These are also known as voluntary muscles.
- (b) Visceral Muscles or Smooth Muscles - These are located in inner wall of hollow visceral organ, smooth in appearance and their activity are not under control of voluntary nervous system. They are called involuntry muscles.
- (c) Cardiac Muscles - The muscles of heart, involuntry in nature, striated and branched, These are uninucleated.
Structure of Myofibril :
- Each myofibril consists of alternate dark and light band.
- Dark band- Contain myosin protein and is called A-band or Anisotoric band.
- Light band- Contain actin protein and is called I Band or Isotropic band.
- I Band is bisected by an elastic fiber called 'Z' line. Actin filament (thin filament) are firmly attached to the 'Z' lines.
- Myosin filament (thick filament) in the 'A' Band are also held together in the middle of T Band by thin fibrous membrane called 'M' line.
- The portion between two successive 'Z' lines is considered as functional unit of contraction and is called a sarcomere.
Structure of Actin and Mycoin Filament :
- 1. Action Filament : An actin filament is made of two 'F' actins which are helically wound to each other. Two filament to tropo myosin protein alos run close to 'F' actins throughout its length. A complex protein Troponin is distributed at regular intervals on topomyosin which mask the actin binding site for myosin.
- 2. Myosin Filament : Each myosin filament is a ploymer of meromyosin. Each meromyosion has two components- a globular head with a short arem and a tail. Head is made of heavy meromyosin while tail is made of light meromyosin. The head with its short arm project outward at regular distance and angle form each other and is known as corss arm. The head has an active site for actin and binding site for ATP.
Red Muscle Fibres :
- These are red in colour due to presence of high content of Myoglobin.
- These contain plenty of mitochondria.
- Sarcoplasmic reticulum is less in these fibres.
- Show slow but sustained contraction for longer periods.
White Muscle Fibres :
- These are pale or whitish due to presence of less content of myoglobin.
- These contain fewer mitochondria
- Sarcoplasmic reticulum is more high
- During stemous exercise, lactic acid accumulates in large quantity so muscle fatigues.
Mechanism or Muscle Contraction : Sliding Filament Theory
- The contraction of muscle fiber takes place by the sliding of action (thin filament) on myosin (thick filament)
- Muscle contraction is initiated by a signal sent by the CNS via a motor neuron.
- Impulse from motor nerve stimulates a muscles fibre at neuro muscular junctions.
- Neurotransmitter releases here which generates an action potential in sarcolema.
- This causes release of Ca++ into sarcoplasm. These Ca++ binds with troponin, thereby remove masking of active site.
- Myosin head binds to exposed active site on actin to form a corss bridge, utilising energy from ATP hydolysis,
- This pulls the actin filament towards the centre of 'A' band.
- 'Z' lines also pulled inward thereby causing a shortening of sarcomore i.e., contraction.
- I band get reduced, whereas the 'A' band retain the length.
- During relexation, the cross bridge between the actin and myosin break. Ca++ pumped back to sarcoplasmic cisternae. Actin filament slide out of 'A' band and length of I band increase. This returns the muscle to its original state.
Vertebral Formulae of Man C7T12L5S(5)C(4)=33 :
